HTo avoid weight gain New research suggests that those at risk of developing obesity due to genetics need to exercise even more than people at average or low risk if they want to protect themselves from the disease. All this data was published in JAMA Network Open. Discuss© CC0 Public Domain
To conduct the study, scientists used data on activities, clinical and genetic data from the All of Us Program of the National Institutes of Health. Their goal was to study the association of genetic risk with a higher body mass index and the level of physical activity needed to reduce the risk of obesity.
The new study included 3,124 middle-aged, non-obese participants. They had a Fitbit device and walked an average of 8,326 steps per day for an average of more than five years. Over the entire observation period, the incidence of obesity increased from 13% to 43% in the groups with the lowest and highest polygenic risk.
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According to the study, people with a polygenic risk score in the 75th percentile need to exercise an average of 2280 more steps per day (total 11,020 steps per day) compared with those with a risk score in the 50th percentile. Then these people will have a comparable risk of obesity.
The experts also found that people with a baseline body mass index of 22, 24, 26 and 28, who were in the 75th percentile of the polygenic risk scale, need to undergo a day of an additional 3460, 4430, 5380 and 6350 steps, respectively, to have a comparable risk of obesity to people at the 25th percentile.
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