And tested in miceA research group at the University of Texas at San Antonio has successfully developed an innovative inhibitor that promises to fight obesity and potentially prevent heart disease. “PfUsGslq” title=”Scientists have created a drug for weight loss without exercise” alt=”Scientists have created a drug for weight loss without exercise” Scientists have created a drug for weight loss without exercise />
UTSA is able to stop the activity of P450 8B1, the enzyme that creates cholic acid in the body. This inhibition, in turn, reduces the absorption of cholesterol. This process may hold the key to treating obesity-related metabolic disorders and other obesity-related diseases such as heart disease and diabetes.
In the study, mice were fed an inhibitor within seven days. The result was a decrease in the blood glucose levels of the mice – despite being fed a diet high in fat and sucrose – with no change in body weight. The results demonstrate how the P450 8B1 inhibitor can lead to a healthier metabolic profile and its potential could lead to the development of a therapeutic strategy to treat obesity-related insulin resistance. preventing obesity could improve quality of life worldwide, scientists say.
Source: Science Daily