A pill that replaces the gym, is closer to reality

Most people are very lazy which is easier to wrinkle her nose, looking at your kilos in the mirror than still decide to go to the gym and try to get in shape. Pharmaceutical corporations are well aware, it is not the first year working to create a drug to replace the lazy mankind grueling workout. It and is clear: drink the pill and without any additional stress tightened his belly and saggy side. Just a fairy tale! And this tale, it seems, sooner or later, everything has come to life.

A group of scientists from the California Institute of biological research Salk made a very important discovery in this direction. In the process of feeding laboratory mice a special chemical compound, it was found that rodents under the influence of the drug are able to run a 70% greater distance than without it. In fact, it is not about a pill that replaces the gym. But a method was found to significantly increase physical endurance. The study is continued by another project team, aimed at studying the processes occurring in the body during a long run.

By identifying a chemical compound that activates the gene responsible for the resistance to weight gain and reacting to the insulin produced from long distance runners, scientists have been able to use this knowledge to create a unique drug. Reprogramming software an the metabolic processes of the organism, the compound allowed mice that were previously able to run for 160 minutes to hold in a given rhythm as much as 270 minutes. Increase of more than 100 minutes impressed seasoned scientists. Man, that is so to increase the load during exercise, it would take more than one week of hard training. And the mouse just took the “cure” and become professional runners.

Another important discovery was the fact that the burning of fat in the body under load is not a result of the fill ending stamina, but only a compensatory mechanism to maintain glucose, so important for proper functioning of the brain. That is saving of glucose can dramatically increase the stamina. Now researchers from the Salk Institute are working to create another medication. This time they plan to enhance the fat burning by activation of the desired gene while suppressing the other gene responsible for burning carbohydrates for energy. Simply put, their next drug will allow the body to draw energy directly from fat without additional exercise. And this is much closer to the dream of humanity, than some kind of “power endurance”.

Tablet, over which a team of researchers in the future will be able to help not only for lazy people with excess weight, but also, for example, patients with type II diabetes, partially paralyzed patients whose muscles gradually atrophy, and many others. But while this is only a science project that is still far from realization.

A pill that replaces the gym, is closer to reality
Sergey Grey


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